Sifat Fisik Farmaseutik Tablet Hisap Herbal Yang Menggunakan PVP K-30 Dan Gom Arab Sebagai Pengikat
Abstract
Tablets are pharmaceutical preparations that are most widely used by the public compared to other pharmaceutical preparations. One type of tablet is lozenges which are solid preparations containing one or more medicinal ingredients, generally with flavorful and sweet ingredients, which can make the tablet dissolve or disintegrate slowly in the mouth. Polyvinyl pyrylone K-30 (PVP K-30) binder has an advantage over other binders, as it can increase the hardness of tablets, making tablets a compact preparation. Arabic gum also has good flow properties, pharmacologically inert, has good compressibility and compactness. The purpose of the review is to determine the pharmaceutical properties of herbal lozenges that use PVP K-30 and Arabic gum as binders. The method used in reviewing this review is an electronic literature study by accessing journal search sites related to the keyword " PVP K-30 lozenges and gum arabic lozenges". Binder material as one of the ingredients needed in lozenges because the binder can determine the level of hardness, brittleness and destruction time of lozenges. PVP binders and gum arabic are examples of binders that have good flow properties and stationary angles, and for hardness PVP tablets are good binders, but if the concentration used is high then the brittleness level is reduced.
References
[2] D. E. Rina, A. G. Samudra, and D. Dominica, “Pengaruh Variasi Konsentrasi Polivinil Pirolidon Sebagai Bahan Pengikat Pada Formulasi Tablet Ekstrak Alga Coklat (Sargassum sp.),” J. Farm. Indones., vol. 03, no. 2, pp. 1–10, 2022.
[3] P. S. Farmasi and U. Pakuan, “Erni Rustiani, Kyky Widayanti, Cantika Zaddana 2022,” vol. IX, no. 1, pp. 63–70, 2022.
[4] Nuraisyah and G. I. Dalimunthe, “FORMULASI DAN EVALUASI SEDIAAN TABLET HISAP DARI SARI JAGUNG (Zea mays L.) DENGAN JENIS PENGIKAT GOM ARAB DAN PUTIH TELUR,” FARMASAINKES J. Farm. SAINS, dan Kesehat., vol. 1, no. 2, pp. 133–141, 2022, doi: 10.32696/fjfsk.v1i2.1108.
[5] E. Rustiani, D. Indriati, and L. Actia, “Formulasi Tablet Hisap Campuran Katekin Gambir Dan Jahe Dengan Jenis Pengikat Pvp Dan Gom Arab,” J. Fitofarmaka Indones., vol. 6, no. 1, pp. 334–339, 2019, doi: 10.33096/jffi.v6i1.465.
[6] R. Aprinita and I. Gusmayadi, “Rahmani Aprinita, Inding Gusmayadi, Priyanto Jurusan Farmasi Fakultas Farmasi dan Sains UHAMKA Jakarta,” 2022.
[7] Y. L. Saputri, D. Nawangsari, and G. Samodra, “Formulasi dan Evaluasi Tablet Hisap Ekstrak Kulit Pisang Raja (Musa X paradisiaca L.) Menggunakan Polivinil Pirolidon (PVP),” J. Mandala Pharmacon Indones., vol. 8, no. 2, pp. 262–274, 2022, doi: 10.35311/jmpi.v8i2.249.
[8] A. Wahyuni, “Review Artikel : Analisis Formulasi Dan Evaluasi Dalam Penggunaan Variasi Bahan Tambahan Pada Lozenges ( Tablet Hisap ),” vol. 3, pp. 9017–9029, 2023.
[9] M. Rijal, A. Buang, and S. Prayitno, “Pengaruh Konsentrasi PVP K-30 Sebagai Bahan Pengikat Terhadap Mutu Fisik Tablet Ekstrak Daun Tekelan (Chromolaena odorata L.),” J. Kesehat. Yamasi Makassar, vol. 6, no. 1, pp. 98–111, 2022, [Online]. Available: http://journal.yamasi.ac.id
[10] A. Pujiastuti, P. Maya Octasari, S. Setyorini, and P. Katolik Mangunwijaya, “Tablet Hisap Sari Buah Tomat (Licopersicon esculentum Mill.) sebagai Penangkal Radikal Bebas Tomato’s Lozenges (Licopersicon esculentum Mill.) As Antioxidant,” IJMS-Indonesian J. Med. Sci., vol. 6, no. 2, pp. 18–24, 2019, [Online]. Available: http://www.ejournal.ijmsbm.org/index.php/ijms/article/view/181
[11] M. Nabil, Meliyana, and Purgiyanti “ Formulasi dan Uji Sifat Fisik Tablet Ekstrak Daun Pepaya (Carica papaya L.) Dengan Kombinasi Gom arab HPMC Sebagai Pengikat. Jurnal Ilmiah Farmasi. Vol. x.No. x (1-11), 2021.